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β-Cyclodextrin as a Functional Excipient Used for Enhancing the Diminazene Aceturate Bioavailability
In this study, we proposed formulations of diminazene aceturate (DA) designed to improve its bioavailability and to maximize the therapeutic index in animals by overcoming the rapid degradation under the acidic pH of the stomach. An important consequence is the fact that its amount in the bloodstrea...
Autores principales: | Marangoci, Narcisa, Timpu, Daniel, Corciova, Andreia, Mircea, Cornelia, Petrovici, Anca-Roxana, Nicolescu, Alina, Ursu, Elena-Laura, Nastasa, Valentin, Bostanaru, Andra-Cristina, Mares, Mihai, Pertea, Mihaela, Pinteala, Mariana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630424/ https://www.ncbi.nlm.nih.gov/pubmed/31234525 http://dx.doi.org/10.3390/pharmaceutics11060295 |
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