Methods to Discover and Evaluate Proteasome Small Molecule Stimulators

Protein accumulation has been identified as a characteristic of many degenerative conditions, such as neurodegenerative diseases and aging. In most cases, these conditions also present with diminished protein degradation. The ubiquitin-proteasome system (UPS) is responsible for the degradation of th...

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Detalles Bibliográficos
Autores principales: Coleman, Rachel A., Trader, Darci J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630500/
https://www.ncbi.nlm.nih.gov/pubmed/31242677
http://dx.doi.org/10.3390/molecules24122341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630500/
https://www.ncbi.nlm.nih.gov/pubmed/31242677
http://dx.doi.org/10.3390/molecules24122341

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