Antiplasmodial Activity and In Vivo Bio-Distribution of Chloroquine Molecules Released with a 4-(4-Ethynylphenyl)-Triazole Moiety from Organometallo-Cobalamins

We have explored the possibility of using organometallic derivatives of cobalamin as a scaffold for the delivery of the same antimalarial drug to both erythro- and hepatocytes. This hybrid molecule approach, intended as a possible tool for the development of multi-stage antimalarial agents, pivots o...

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Detalles Bibliográficos
Autores principales: Rossier, Jeremie, Nasiri Sovari, Sara, Pavic, Aleksandar, Vojnovic, Sandra, Stringer, Tameryn, Bättig, Sarah, Smith, Gregory S., Nikodinovic-Runic, Jasmina, Zobi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630517/
https://www.ncbi.nlm.nih.gov/pubmed/31234469
http://dx.doi.org/10.3390/molecules24122310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630517/
https://www.ncbi.nlm.nih.gov/pubmed/31234469
http://dx.doi.org/10.3390/molecules24122310

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