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Cellular Senescence and Iron Dyshomeostasis in Alzheimer’s Disease

Iron dyshomeostasis is a feature of Alzheimer’s disease (AD). The impact of iron on AD is attributed to its interactions with the central proteins of AD pathology (amyloid precursor protein and tau) and/or through the iron-mediated generation of prooxidant molecules (e.g., hydroxyl radicals). Howeve...

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Detalles Bibliográficos
Autores principales: Masaldan, Shashank, Belaidi, Abdel Ali, Ayton, Scott, Bush, Ashley I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630536/
https://www.ncbi.nlm.nih.gov/pubmed/31248150
http://dx.doi.org/10.3390/ph12020093