A Photocleavable Amphiphilic Prodrug Self-Assembled Nanoparticles with Effective Anticancer Activity In Vitro

Accelerating degradation of prodrug is an effective strategy for improving the pharmacological action. A photocleavable amphiphilic prodrug of methotrexate-coumarin derivative-PEG conjugates (MTX-AMC-PEG) with photo-triggered breakage to release clinical drug under laser irradiation was fabricated a...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Li, Guotao, Liu, Qihong, Liang, Yan, Liu, Miaochang, Wu, Huayue, Gao, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630543/
https://www.ncbi.nlm.nih.gov/pubmed/31195730
http://dx.doi.org/10.3390/nano9060860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630543/
https://www.ncbi.nlm.nih.gov/pubmed/31195730
http://dx.doi.org/10.3390/nano9060860

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