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Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins

Porcine circovirus type 2 (PCV2) is the etiological agent of porcine circovirus diseases and porcine circovirus-associated diseases (PCVDs/PCVADs). However, the pathogenesis of PCV2 is not fully understood. We previously found that 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is negativel...

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Detalles Bibliográficos
Autores principales: Ouyang, Ting, Niu, Guyu, Zhang, Yifang, Liu, Xiaohua, Zhang, Xinwei, Zhang, Shiqi, Geng, Yulu, Pang, Daxin, Ouyang, Hongsheng, Ren, Linzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630565/
https://www.ncbi.nlm.nih.gov/pubmed/31212640
http://dx.doi.org/10.3390/v11060544