Insights into the Molecular Mechanisms of Eg5 Inhibition by (+)-Morelloflavone

(+)-Morelloflavone (MF) is an antitumor biflavonoid that is found in the Garcinia species. Recently, we reported MF as a novel inhibitor of ATPase and microtubules-gliding activities of the kinesin spindle protein (Eg5) in vitro. Herein, we provide dynamical insights into the inhibitory mechanisms o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogunwa, Tomisin Happy, Laudadio, Emiliano, Galeazzi, Roberta, Miyanishi, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630617/
https://www.ncbi.nlm.nih.gov/pubmed/30995725
http://dx.doi.org/10.3390/ph12020058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630617/
https://www.ncbi.nlm.nih.gov/pubmed/30995725
http://dx.doi.org/10.3390/ph12020058

Ejemplares similares