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Bioengineering an Artificial Human Blood–Brain Barrier in Rodents

Our group has recently created a novel in-vivo human brain organoid vascularized with human iPSC-derived endothelial cells. In this review article, we discuss the challenges of creating a perfused human brain organoid model in an immunosuppressed rodent host and discuss potential applications for ne...

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Detalles Bibliográficos
Autores principales: Kamal, Kimia, Waldau, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630638/
https://www.ncbi.nlm.nih.gov/pubmed/31052208
http://dx.doi.org/10.3390/bioengineering6020038