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Bioengineering an Artificial Human Blood–Brain Barrier in Rodents
Our group has recently created a novel in-vivo human brain organoid vascularized with human iPSC-derived endothelial cells. In this review article, we discuss the challenges of creating a perfused human brain organoid model in an immunosuppressed rodent host and discuss potential applications for ne...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630638/ https://www.ncbi.nlm.nih.gov/pubmed/31052208 http://dx.doi.org/10.3390/bioengineering6020038 |