Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors

A new series of thiazolo[3,2-a]pyrimidine bromide salt derivatives 7a–d were synthesized from 3,4-dihydropyrimidinethione precursors. The target compounds were fully characterized by 1D- and 2D-NMR, high resolution ESI-MS/MS and single crystal X-ray diffraction analysis, which confirmed a regioselec...

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Detalles Bibliográficos
Autores principales: Mahgoub, Mohamed Y., Elmaghraby, Awatef M., Harb, Abd-Elfttah A., Ferreira da Silva, João L., Justino, Gonçalo C., Marques, M. Matilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630738/
https://www.ncbi.nlm.nih.gov/pubmed/31234400
http://dx.doi.org/10.3390/molecules24122306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630738/
https://www.ncbi.nlm.nih.gov/pubmed/31234400
http://dx.doi.org/10.3390/molecules24122306

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