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Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors
A new series of thiazolo[3,2-a]pyrimidine bromide salt derivatives 7a–d were synthesized from 3,4-dihydropyrimidinethione precursors. The target compounds were fully characterized by 1D- and 2D-NMR, high resolution ESI-MS/MS and single crystal X-ray diffraction analysis, which confirmed a regioselec...
Autores principales: | Mahgoub, Mohamed Y., Elmaghraby, Awatef M., Harb, Abd-Elfttah A., Ferreira da Silva, João L., Justino, Gonçalo C., Marques, M. Matilde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630738/ https://www.ncbi.nlm.nih.gov/pubmed/31234400 http://dx.doi.org/10.3390/molecules24122306 |
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