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Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase

Inhibition of α-amylase and α-glucosidase by specified synthetic compounds during the digestion of starch helps control post-prandial hyperglycemia and could represent a potential therapy for type II diabetes mellitus. A new series of spiroheterocyclic compounds bearing oxindole/benzofuran/pyrrolidi...

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Detalles Bibliográficos
Autores principales: Altowyan, Mezna Saleh, Barakat, Assem, Al-Majid, Abdullah Mohammed, Al-Ghulikah, H.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630796/
https://www.ncbi.nlm.nih.gov/pubmed/31242688
http://dx.doi.org/10.3390/molecules24122342