Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

The amyloid-β (Aβ) peptide and tau protein are thought to play key neuropathogenic roles in Alzheimer’s disease (AD). Both Aβ and tau self-assemble to form the two major pathological hallmarks of AD: amyloid plaques and neurofibrillary tangles, respectively. In this review, we show that naturally oc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Qiuchen, Kebede, Micheal T., Kemeh, Merc M., Islam, Saadman, Lee, Bethany, Bleck, Stuart D., Wurfl, Liliana A., Lazo, Noel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630797/
https://www.ncbi.nlm.nih.gov/pubmed/31234523
http://dx.doi.org/10.3390/molecules24122316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630797/
https://www.ncbi.nlm.nih.gov/pubmed/31234523
http://dx.doi.org/10.3390/molecules24122316

Ejemplares similares