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The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration

The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish model system to study the effects of a synthetic, orally bioavailable glycogen synthase kinase-3β (GSK3β) inhibitor LSN 2105786, which activates Wnt signaling during bone he...

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Detalles Bibliográficos
Autores principales: Sarmah, Swapnalee, Curtis, Courtney, Mahin, Jennifer, Farrell, Mark, Engler, Thomas A., Sanchez-Felix, Manuel V., Sato, Masahiko, Ma, Yanfai Linda, Chu, Shaoyou, Marrs, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630808/
https://www.ncbi.nlm.nih.gov/pubmed/31010223
http://dx.doi.org/10.3390/biomedicines7020030