Cargando…

The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration

The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish model system to study the effects of a synthetic, orally bioavailable glycogen synthase kinase-3β (GSK3β) inhibitor LSN 2105786, which activates Wnt signaling during bone he...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarmah, Swapnalee, Curtis, Courtney, Mahin, Jennifer, Farrell, Mark, Engler, Thomas A., Sanchez-Felix, Manuel V., Sato, Masahiko, Ma, Yanfai Linda, Chu, Shaoyou, Marrs, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630808/ https://www.ncbi.nlm.nih.gov/pubmed/31010223 http://dx.doi.org/10.3390/biomedicines7020030

Ejemplares similares

The Genius of the Zebrafish Model: Insights on Development and Disease
por: Marrs, James A., et al.
Publicado: (2021)

Zebrafish as a Vertebrate Model System to Evaluate Effects of Environmental Toxicants on Cardiac Development and Function
por: Sarmah, Swapnalee, et al.
Publicado: (2016)

Embryonic Ethanol Exposure Affects Early- and Late-Added Cardiac Precursors and Produces Long-Lasting Heart Chamber Defects in Zebrafish
por: Sarmah, Swapnalee, et al.
Publicado: (2017)

Ethanol Effects on Early Developmental Stages Studied Using the Zebrafish
por: Manikandan, Priyadharshini, et al.
Publicado: (2022)

Retinal Wnt signaling defect in a zebrafish fetal alcohol spectrum disorder model
por: Muralidharan, Pooja, et al.
Publicado: (2018)

Embryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in Zebrafish
por: Sarmah, Swapnalee, et al.
Publicado: (2016)

Elf3 deficiency during zebrafish development alters extracellular matrix organization and disrupts tissue morphogenesis
por: Sarmah, Swapnalee, et al.
Publicado: (2022)

Marijuana and Opioid Use during Pregnancy: Using Zebrafish to Gain Understanding of Congenital Anomalies Caused by Drug Exposure during Development
por: Sarmah, Swapnalee, et al.
Publicado: (2020)

The art of fin regeneration in zebrafish
por: Pfefferli, Catherine, et al.
Publicado: (2015)

Embryonic ethanol exposure alters expression of sox2 and other early transcripts in zebrafish, producing gastrulation defects
por: Sarmah, Swapnalee, et al.
Publicado: (2020)

Fetal Alcohol Spectrum Disorder (FASD) Associated Neural Defects: Complex Mechanisms and Potential Therapeutic Targets
por: Muralidharan, Pooja, et al.
Publicado: (2013)

Denervation impairs regeneration of amputated zebrafish fins
por: Simões, Mariana G, et al.
Publicado: (2014)

Transcriptional Profiling of Caudal Fin Regeneration in Zebrafish
por: Schebesta, Michael, et al.
Publicado: (2006)

Shikonin Inhibits Fin Regeneration in Zebrafish Larvae
por: Cao, Zigang, et al.
Publicado: (2022)

Macrophages modulate adult zebrafish tail fin regeneration
por: Petrie, Timothy A., et al.
Publicado: (2014)

Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses
por: Sehring, Ivonne, et al.
Publicado: (2022)

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin
por: Hyde, David R., et al.
Publicado: (2012)

Specific NuRD components are required for fin regeneration in zebrafish
por: Pfefferli, Catherine, et al.
Publicado: (2014)

Zebrafish fin regeneration after cryoinjury-induced tissue damage
por: Chassot, Bérénice, et al.
Publicado: (2016)

TNF signaling and macrophages govern fin regeneration in zebrafish larvae
por: Nguyen-Chi, Mai, et al.
Publicado: (2017)

Hyaluronic acid synthesis is required for zebrafish tail fin regeneration
por: Ouyang, Xiaohu, et al.
Publicado: (2017)

Regrowth of zebrafish caudal fin regeneration is determined by the amputated length
por: Uemoto, Toshiaki, et al.
Publicado: (2020)

Impaired fin regeneration and angiogenesis in aged zebrafish and turquoise killifish
por: Örling, Johanna, et al.
Publicado: (2023)

Fgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration
por: Bouzaffour, Mohamed, et al.
Publicado: (2009)

In Vivo Cell and Tissue Dynamics Underlying Zebrafish Fin Fold Regeneration
por: Mateus, Rita, et al.
Publicado: (2012)

Correction to: TNF signaling and macrophages govern fin regeneration in zebrafish larvae
por: Nguyen-Chi, Mai, et al.
Publicado: (2018)

Suppressive effects of valproic acid on caudal fin regeneration in adult zebrafish
por: Lee, Yunkyoung, et al.
Publicado: (2020)

Distinct pro-vigilant profile induced in rats by the mGluR5 potentiator LSN2814617
por: Loomis, Sally, et al.
Publicado: (2015)

PET quantification of brain O-GlcNAcase with [(18)F]LSN3316612 in healthy human volunteers
por: Lee, Jae-Hoon, et al.
Publicado: (2020)

Impaired caudal fin‐fold regeneration in zebrafish deficient for the tumor suppressor Pten
por: Hale, Alexander James, et al.
Publicado: (2017)

The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin
por: Pfefferli, Catherine, et al.
Publicado: (2017)

Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration
por: Wu, Wei, et al.
Publicado: (2017)

Glucocorticoid Treatment Leads to Aberrant Ion and Macromolecular Transport in Regenerating Zebrafish Fins
por: Schmidt, Johannes R., et al.
Publicado: (2019)

Zebrafish caudal fin as a model to investigate the role of probiotics in bone regeneration
por: Sojan, Jerry Maria, et al.
Publicado: (2022)

Regulatory T cells regulate blastemal proliferation during zebrafish caudal fin regeneration
por: Hui, Subhra P., et al.
Publicado: (2022)

Sec24D-Dependent Transport of Extracellular Matrix Proteins Is Required for Zebrafish Skeletal Morphogenesis
por: Sarmah, Swapnalee, et al.
Publicado: (2010)

Glycogen Synthase Kinase-3
por: Crouch, Peter, et al.
Publicado: (2011)

Region- and voxel-based quantification in human brain of [(18)F]LSN3316612, a radioligand for O-GlcNAcase
por: Lee, Jae-Hoon, et al.
Publicado: (2021)

Control of Glycogen Content in Retina: Allosteric Regulation of Glycogen Synthase
por: Osorio-Paz, Ixchel, et al.
Publicado: (2012)

Glycogen synthase kinase 3: a crucial regulator of axotomy-induced axon regeneration
por: Liu, Jinlian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vp7b1pk1k4hj6nan1ba2j7plep