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Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

Nucleic acid packed within virus-like particles (VLPs) is shown to shape the immune response and to induce stronger B cell responses in different immunisation models. Here, using a VLP displaying the highly conserved extracellular domain of the M2 protein (M2e) from the influenza viruses as an antig...

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Detalles Bibliográficos
Autores principales: C. Gomes, Ariane, Roesti, E. S., El-Turabi, Aadil, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630894/
https://www.ncbi.nlm.nih.gov/pubmed/31167472
http://dx.doi.org/10.3390/vaccines7020047