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Multi-Color Single-Molecule Imaging Uncovers Extensive Heterogeneity in mRNA Decoding
mRNA translation is a key step in decoding genetic information. Genetic decoding is surprisingly heterogeneous because multiple distinct polypeptides can be synthesized from a single mRNA sequence. To study translational heterogeneity, we developed the MoonTag, a fluorescence labeling system to visu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630898/ https://www.ncbi.nlm.nih.gov/pubmed/31178119 http://dx.doi.org/10.1016/j.cell.2019.05.001 |