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Development and In Vitro-In Vivo Evaluation of a Novel Sustained-Release Loxoprofen Pellet with Double Coating Layer

This study aimed to develop a novel sustained release pellet of loxoprofen sodium (LXP) by coating a dissolution-rate controlling sub-layer containing hydroxypropyl methyl cellulose (HPMC) and citric acid, and a second diffusion-rate controlling layer containing aqueous dispersion of ethyl cellulose...

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Detalles Bibliográficos
Autores principales: Wan, Dongwei, Zhao, Min, Zhang, Jingjing, Luan, Libiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631012/
https://www.ncbi.nlm.nih.gov/pubmed/31195668
http://dx.doi.org/10.3390/pharmaceutics11060260