CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells

Cyclin dependent kinase 11 (CDK11) is a protein kinase that regulates RNA transcription, pre-mRNA splicing, mitosis, and cell death. Targeting of CDK11 expression levels is effective in the experimental treatment of breast and other cancers, but these data are lacking in melanoma. To understand CDK1...

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Detalles Bibliográficos
Autores principales: Ahmed, Rehana L., Shaughnessy, Daniel P., Knutson, Todd P., Vogel, Rachel I., Ahmed, Khalil, Kren, Betsy T., Trembley, Janeen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631185/
https://www.ncbi.nlm.nih.gov/pubmed/30987032
http://dx.doi.org/10.3390/ph12020050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631185/
https://www.ncbi.nlm.nih.gov/pubmed/30987032
http://dx.doi.org/10.3390/ph12020050

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