Chain-Branched Polyhydroxylated Octahydro-1H-Indoles as Potential Leads against Lysosomal Storage Diseases

Here, the synthesis and glycosidase inhibition properties of the two first known 3-ethyloctahydro-1H-indole-4,5,6-triols are reported. This study shows the transformation of d-glucose into polyhydroxylated 1-(2-nitrocyclohexane) acetaldehydes, followed by a protocol involving the formation of the az...

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Detalles Bibliográficos
Autores principales: Estévez, Juan C., González, Marcos A., Villaverde, M. Carmen, Hirokami, Yuki, Kato, Atsushi, Sussman, Fredy, Reza, David, Estévez, Ramón J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631223/
https://www.ncbi.nlm.nih.gov/pubmed/30934879
http://dx.doi.org/10.3390/ph12020047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631223/
https://www.ncbi.nlm.nih.gov/pubmed/30934879
http://dx.doi.org/10.3390/ph12020047

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