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Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol

The avian leukosis virus subgroup J (ALV-J) belongs to the chicken retrovirus that causes enormous economic losses in the poultry industry. Interferon-stimulated genes (ISGs) are critical for controlling virus infections. Here, we identified 897 type I ISGs induced by interferon-α (IFN-α) in chicken...

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Detalles Bibliográficos
Autores principales: Xie, Tingting, Feng, Min, Dai, Manman, Mo, Guodong, Ruan, Zhuohao, Wang, Guiyan, Shi, Meiqing, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631237/
https://www.ncbi.nlm.nih.gov/pubmed/31151272
http://dx.doi.org/10.3390/v11060498