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SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis

Atherosclerosis, which underlies life-threatening cardiovascular disorders including myocardial infarction and stroke(1), is initiated by low density lipoprotein cholesterol (LDL) passage into the artery wall and engulfment by macrophages, leading to foam cell formation and lesion development(2, 2,...

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Detalles Bibliográficos
Autores principales: Huang, Linzhang, Chambliss, Ken L., Gao, Xiaofei, Yuhanna, Ivan S., Behling-Kelly, Erica, Bergaya, Sonia, Ahmed, Mohamed, Michaely, Peter, Luby-Phelps, Kate, Darehshouri, Anza, Xu, Lin, Fisher, Edward A., Ge, Woo-Ping, Mineo, Chieko, Shaul, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631346/
https://www.ncbi.nlm.nih.gov/pubmed/31019307
http://dx.doi.org/10.1038/s41586-019-1140-4