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SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis
Atherosclerosis, which underlies life-threatening cardiovascular disorders including myocardial infarction and stroke(1), is initiated by low density lipoprotein cholesterol (LDL) passage into the artery wall and engulfment by macrophages, leading to foam cell formation and lesion development(2, 2,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631346/ https://www.ncbi.nlm.nih.gov/pubmed/31019307 http://dx.doi.org/10.1038/s41586-019-1140-4 |