Set-Up and Validation of a High Throughput Screening Method for Human Monoacylglycerol Lipase (MAGL) Based on a New Red Fluorescent Probe

Monoacylglycerol lipase (MAGL) is a serine hydrolase that has a key regulatory role in controlling the levels of 2-arachidonoylglycerol (2-AG), the main signaling molecule in the endocannabinoid system. Identification of selective modulators of MAGL enables both to provide new tools for investigatin...

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Detalles Bibliográficos
Autores principales: Miceli, Matteo, Casati, Silvana, Ottria, Roberta, Di Leo, Simone, Eberini, Ivano, Palazzolo, Luca, Parravicini, Chiara, Ciuffreda, Pierangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631453/
https://www.ncbi.nlm.nih.gov/pubmed/31208066
http://dx.doi.org/10.3390/molecules24122241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631453/
https://www.ncbi.nlm.nih.gov/pubmed/31208066
http://dx.doi.org/10.3390/molecules24122241

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