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In Silico Insights into HIV-1 Vpu-Tetherin Interactions and Its Mutational Counterparts

Tetherin, an interferon-induced host protein encoded by the bone marrow stromal antigen 2 (BST2/CD317/HM1.24) gene, is involved in obstructing the release of many retroviruses and other enveloped viruses by cross-linking the budding virus particles to the cell surface. This activity is antagonized i...

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Detalles Bibliográficos
Autores principales: Sneha, Patil, Shah, Urmi, Balaji, Seetharaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631454/
https://www.ncbi.nlm.nih.gov/pubmed/31234536
http://dx.doi.org/10.3390/medsci7060074