Heterologous Expression of Ilicicolin H Biosynthetic Gene Cluster and Production of a New Potent Antifungal Reagent, Ilicicolin J

Ilicicolin H is a broad-spectrum antifungal agent targeting mitochondrial cytochrome bc1 reductase. Unfortunately, ilicicolin H shows reduced activities in vivo. Here, we report our effort on the identification of ilicicolin H biosynthetic gene cluster (BGC) by genomic sequencing a producing strain,...

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Detalles Bibliográficos
Autores principales: Lin, Xiaojing, Yuan, Siwen, Chen, Senhua, Chen, Bin, Xu, Hui, Liu, Lan, Li, Huixian, Gao, Zhizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631495/
https://www.ncbi.nlm.nih.gov/pubmed/31216742
http://dx.doi.org/10.3390/molecules24122267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631495/
https://www.ncbi.nlm.nih.gov/pubmed/31216742
http://dx.doi.org/10.3390/molecules24122267

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