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Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. Aberrant regulation of the activation of the transcription factor NF-κB i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631534/ https://www.ncbi.nlm.nih.gov/pubmed/31137887 http://dx.doi.org/10.3390/biomedicines7020040 |