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Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model

The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. Aberrant regulation of the activation of the transcription factor NF-κB i...

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Detalles Bibliográficos
Autores principales: Benary, Uwe, Wolf, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631534/
https://www.ncbi.nlm.nih.gov/pubmed/31137887
http://dx.doi.org/10.3390/biomedicines7020040