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Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes

Angiogenesis is a process of new blood vessel formation, which plays a significant role in carcinogenesis and the development of diseases associated with pathological neovascularization. An important role in the regulation of angiogenesis belongs to several key pathways such as VEGF-pathways, TGF-β-...

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Detalles Bibliográficos
Autores principales: Egorova, Anna A., Shtykalova, Sofia V., Maretina, Marianna A., Sokolov, Dmitry I., Selkov, Sergei A., Baranov, Vladislav S., Kiselev, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631635/
https://www.ncbi.nlm.nih.gov/pubmed/31174285
http://dx.doi.org/10.3390/pharmaceutics11060261