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Fabrication of Polymer Micelles with Zwitterionic Shell and Biodegradable Core for Reductively Responsive Release of Doxorubicin

To achieve a high stability in physiological environment and rapid intracellular drug release, a biodegradable zwitterionic triblock copolymer with a disulfide-linked poly-ε-caprolactone and polycarboxybetaine methacrylate (PCBMA-SS-PCL-SS-PCBMA) was prepared for micellar carrier to delivery doxorub...

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Detalles Bibliográficos
Autores principales: Jiang, Junting, Li, Junbo, Zhou, Biyu, Niu, Chaohuang, Wang, Wendi, Wu, Wenlan, Liang, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631697/
https://www.ncbi.nlm.nih.gov/pubmed/31181866
http://dx.doi.org/10.3390/polym11061019