Assessment of Nonnucleoside Inhibitors Binding to HIV-1 Reverse Transcriptase Using HYDE Scoring

In this study, 48 inhibitors were docked to 107 allosteric centers of human immunodeficiency virus 1 (HIV-1) reverse transcriptase from the Protein Data Bank (PDB). Based on the average binding scores, quantitative structure-activity relationship (QSAR) equations were constructed in order to elucida...

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Detalles Bibliográficos
Autores principales: Paneth, Agata, Płonka, Wojciech, Paneth, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631718/
https://www.ncbi.nlm.nih.gov/pubmed/31022835
http://dx.doi.org/10.3390/ph12020064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631718/
https://www.ncbi.nlm.nih.gov/pubmed/31022835
http://dx.doi.org/10.3390/ph12020064

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