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In Vitro and In Vivo Anti-Breast Cancer Activities of Some Newly Synthesized 5-(thiophen-2-yl)thieno-[2,3-d]pyrimidin-4-one Candidates

In this study, some of new thiophenyl thienopyrimidinone derivatives 2–15 were prepared and tested as anti-cancer agents by using thiophenyl thieno[2,3-d]pyrimidinone derivative 2 as a starting material, which was prepared from cyclization of ethyl ester derivative 1 with formamide. Treatment of 2 w...

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Detalles Bibliográficos
Autores principales: Amr, Abd El-Galil E., Ibrahimd, Alhussein A., El-Shehry, Mohamed F., Hosni, Hanaa M., Fayed, Ahmed A., Elsayed, Elsayed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631792/
https://www.ncbi.nlm.nih.gov/pubmed/31212962
http://dx.doi.org/10.3390/molecules24122255