In vitro and in vivo characterization of anti-malarial acylphenoxazine derivatives prepared from basic blue 3

BACKGROUND: Basic blue 3 is a promising anti-malarial lead compound based on the π-delocalized lipophilic cation hypothesis. Its derivatives with nitrogen atoms bonded to carbon atoms at the 3- and 7-positions on the phenoxazine ring were previously shown to exert potent antiprotozoal activity again...

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Detalles Bibliográficos
Autores principales: Tougan, Takahiro, Takahashi, Kazunori, Ikegami-Kawai, Mayumi, Horiuchi, Masako, Mori, Shiho, Hosoi, Maiko, Horii, Toshihiro, Ihara, Masataka, Tsubuki, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631887/
https://www.ncbi.nlm.nih.gov/pubmed/31307493
http://dx.doi.org/10.1186/s12936-019-2873-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631887/
https://www.ncbi.nlm.nih.gov/pubmed/31307493
http://dx.doi.org/10.1186/s12936-019-2873-0

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