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In vitro and in vivo characterization of anti-malarial acylphenoxazine derivatives prepared from basic blue 3
BACKGROUND: Basic blue 3 is a promising anti-malarial lead compound based on the π-delocalized lipophilic cation hypothesis. Its derivatives with nitrogen atoms bonded to carbon atoms at the 3- and 7-positions on the phenoxazine ring were previously shown to exert potent antiprotozoal activity again...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631887/ https://www.ncbi.nlm.nih.gov/pubmed/31307493 http://dx.doi.org/10.1186/s12936-019-2873-0 |