Tripling the Bioavailability of Rosuvastatin Calcium Through Development and Optimization of an In-Situ Forming Nanovesicular System

In situ forming nanovesicular systems (IFNs) were prepared and optimized to improve Rosuvastatin calcium (RC) oral bioavailability through increasing its solubility and dissolution rate. The IFN was composed of Tween(®) 80 (T80), cetyl alcohol (CA), in addition to mannitol or Aerosil 200. A single s...

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Detalles Bibliográficos
Autores principales: Elsayed, Ibrahim, El-Dahmy, Rania Moataz, Elshafeey, Ahmed Hassen, Abd El Gawad, Nabaweya Abdelaziz, El Gazayerly, Omaima Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631901/
https://www.ncbi.nlm.nih.gov/pubmed/31212660
http://dx.doi.org/10.3390/pharmaceutics11060275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631901/
https://www.ncbi.nlm.nih.gov/pubmed/31212660
http://dx.doi.org/10.3390/pharmaceutics11060275

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