Identification of Marek’s Disease Virus VP22 Tegument Protein Domains Essential for Virus Cell-to-Cell Spread, Nuclear Localization, Histone Association and Cell-Cycle Arrest

VP22 is a major tegument protein of alphaherpesviruses encoded by the UL49 gene. Two properties of VP22 were discovered by studying Marek’s disease virus (MDV), the Mardivirus prototype; it has a major role in virus cell-to-cell spread and in cell cycle modulation. This 249 AA-long protein contains...

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Detalles Bibliográficos
Autores principales: Trapp-Fragnet, Laëtitia, Courvoisier, Katia, Rémy, Sylvie, Le Pape, G., Loustalot, Fabien, Denesvre, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631903/
https://www.ncbi.nlm.nih.gov/pubmed/31181775
http://dx.doi.org/10.3390/v11060537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631903/
https://www.ncbi.nlm.nih.gov/pubmed/31181775
http://dx.doi.org/10.3390/v11060537

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