Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti-Mycobacterium ulcerans Natural Product-Derived Compounds

Buruli ulcer is a neglected tropical disease caused by the bacterium Mycobacterium ulcerans. Its virulence is attributed to the dermo-necrotic polyketide toxin mycolactone, whose synthesis is regressed when its iron acquisition system regulated by the iron-dependent regulator (ideR) is deactivated....

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Detalles Bibliográficos
Autores principales: Kwofie, Samuel K., Enninful, Kweku S., Yussif, Jaleel A., Asante, Lina A., Adjei, Mavis, Kan-Dapaah, Kwabena, Tiburu, Elvis K., Mensah, Wilhelmina A., Miller, Whelton A., Mosi, Lydia, Wilson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631925/
https://www.ncbi.nlm.nih.gov/pubmed/31234337
http://dx.doi.org/10.3390/molecules24122299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631925/
https://www.ncbi.nlm.nih.gov/pubmed/31234337
http://dx.doi.org/10.3390/molecules24122299

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