The genetic evolution of metastatic uveal melanoma

Uveal melanoma is a clinically distinct and particularly lethal subtype of melanoma originating from melanocytes in the eye. Here, we performed multi-region DNA sequencing of primary uveal melanomas and their matched metastases from 35 patients. We observed novel driver mutations and established the...

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Detalles Bibliográficos
Autores principales: Shain, A. Hunter, Bagger, Mette M., Yu, Richard, Chang, Darwin, Liu, Shanshan, Vemula, Swapna, Weier, Jingly F., Wadt, Karin, Heegaard, Steffen, Bastian, Boris C., Kiilgaard, Jens F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632071/
https://www.ncbi.nlm.nih.gov/pubmed/31253977
http://dx.doi.org/10.1038/s41588-019-0440-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632071/
https://www.ncbi.nlm.nih.gov/pubmed/31253977
http://dx.doi.org/10.1038/s41588-019-0440-9

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