Cargando…

Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model

Identification of novel molecular adjuvants which can boost and enhance vaccine-mediated immunity and provide dose-sparing potential against complex infectious diseases and for immunotherapy in cancer is likely to play a critical role in the next generation of vaccines. Given the number of challengi...

Descripción completa

Detalles Bibliográficos
Autores principales: Louis, Lumena, Wise, Megan C., Choi, Hyeree, Villarreal, Daniel O., Muthumani, Kar, Weiner, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632123/
https://www.ncbi.nlm.nih.gov/pubmed/31121939
http://dx.doi.org/10.3390/vaccines7020042