Towards On-Demand E. coli-Based Cell-Free Protein Synthesis of Tissue Plasminogen Activator

Stroke is the leading cause of death with over 5 million deaths worldwide each year. About 80% of strokes are ischemic strokes caused by blood clots. Tissue plasminogen activator (tPa) is the only FDA-approved drug to treat ischemic stroke with a wholesale price over $6000. tPa is now off patent alt...

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Detalles Bibliográficos
Autores principales: Yang, Seung-Ook, Nielsen, Gregory H., Wilding, Kristen M., Cooper, Merideth A., Wood, David W., Bundy, Bradley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Benchmark
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632163/
http://dx.doi.org/10.3390/mps2020052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632163/
http://dx.doi.org/10.3390/mps2020052

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