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Rapid, Refined, and Robust Method for Expression, Purification, and Characterization of Recombinant Human Amyloid beta 1-42

Amyloid plaques found in the brains of Alzheimer’s disease patients primarily consists of amyloid beta 1-42 (Aβ42). Commercially, Aβ42 is synthesized using high-throughput peptide synthesizers resulting in the presence of impurities and the racemization of amino acids that affects its aggregation pr...

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Detalles Bibliográficos
Autores principales: Prakash, Priya, Lantz, Travis C., Jethava, Krupal P., Chopra, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632169/
https://www.ncbi.nlm.nih.gov/pubmed/31181684
http://dx.doi.org/10.3390/mps2020048