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A novel tissue-selective β2-adrenoceptor agonist with minimized cardiovascular effects, 5-HOB, attenuates neuropathic pain in mice

OBJECTIVE: 5-HOB is a novel tissue selective, 5-hydroxybenzothiazolone-derived β2 adrenoceptor agonist with minimized cardiovascular effects while retaining efficacy on skeletal muscle in preclinical experiments unlike conventional β2 adrenoceptor agonists, however its effect on the nervous system h...

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Detalles Bibliográficos
Autores principales: Jourdain, Marie, Hatakeyama, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632195/
https://www.ncbi.nlm.nih.gov/pubmed/31307541
http://dx.doi.org/10.1186/s13104-019-4466-y