Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...

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Detalles Bibliográficos
Autores principales: Awakawa, Takayoshi, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632223/
https://www.ncbi.nlm.nih.gov/pubmed/31354873
http://dx.doi.org/10.3762/bjoc.15.157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632223/
https://www.ncbi.nlm.nih.gov/pubmed/31354873
http://dx.doi.org/10.3762/bjoc.15.157

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