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Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis
Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...
Autores principales: | Awakawa, Takayoshi, Abe, Ikuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632223/ https://www.ncbi.nlm.nih.gov/pubmed/31354873 http://dx.doi.org/10.3762/bjoc.15.157 |
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