C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms

Some neurological disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), fragile X syndrome, Huntington's disease, myotonic dystrophy, and various ataxias, can be caused by expansions of short nucleic acid sequence repeats in specific genes. A possible disease...

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Detalles Bibliográficos
Autores principales: Wang, Xueyin, Goodrich, Karen J., Conlon, Erin G., Gao, Jianchao, Erbse, Annette H., Manley, James L., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633194/
https://www.ncbi.nlm.nih.gov/pubmed/31048495
http://dx.doi.org/10.1261/rna.071191.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633194/
https://www.ncbi.nlm.nih.gov/pubmed/31048495
http://dx.doi.org/10.1261/rna.071191.119

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