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Ribosome clearance during RNA interference

In the course of identifying and cleaving RNA, the RNAi machinery must encounter and contend with the megadalton-sized ribosomes that carry out translation. We investigated this interface by examining the fate of actively translated mRNAs subjected to RNAi in C. elegans. Quantifying RNA levels (RNA-...

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Detalles Bibliográficos
Autores principales: Pule, Makena N., Glover, Marissa L., Fire, Andrew Z., Arribere, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633202/
https://www.ncbi.nlm.nih.gov/pubmed/31110136
http://dx.doi.org/10.1261/rna.070813.119