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Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure
Cellular generation of mechanical forces required to close the presumptive spinal neural tube, the ‘posterior neuropore’ (PNP), involves interkinetic nuclear migration (INM) and apical constriction. Both processes change the apical surface area of neuroepithelial cells, but how they are biomechanica...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633395/ https://www.ncbi.nlm.nih.gov/pubmed/31182644 http://dx.doi.org/10.1242/jcs.230300 |