The total flavonoid of Eucommia ulmoides sensitizes human glioblastoma cells to radiotherapy via HIF-α/MMP-2 pathway and activates intrinsic apoptosis pathway

Background: As one of the most common and lethal malignant primary brain tumors, glioblastomas (GBMs) are identified as grade IV neoplasms, the most severe grade, according to WHO classification systems. The outcome of surgery against GBMs is limited since its frequent relapse. Radiotherapy is a cru...

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Detalles Bibliográficos
Autores principales: Wang, Yongsheng, Tan, Xiangru, Li, Song, Yang, Shuilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633463/
https://www.ncbi.nlm.nih.gov/pubmed/31371989
http://dx.doi.org/10.2147/OTT.S210497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633463/
https://www.ncbi.nlm.nih.gov/pubmed/31371989
http://dx.doi.org/10.2147/OTT.S210497

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