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Differential gene expression and AKT targeting in triple negative breast cancer

Background: Metastatic triple negative breast cancer (mTNBC) is a heterogeneous disease with poor prognosis. Molecular evolution of TNBC through chemotherapy selection pressure is well recognized but poorly understood. PI3K/AKT/mTOR is one of the most commonly identified oncogenic-driver pathways in...

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Detalles Bibliográficos
Autores principales: Lin, Feng-Mao, Yost, Susan E., Wen, Wei, Frankel, Paul H., Schmolze, Daniel, Chu, Pei-Guo, Yuan, Yate-Ching, Liu, Zheng, Yim, John, Chen, Zhen, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633890/
https://www.ncbi.nlm.nih.gov/pubmed/31320990
http://dx.doi.org/10.18632/oncotarget.27026