Trimethylamine N-Oxide Exacerbates Cardiac Fibrosis via Activating the NLRP3 Inflammasome

Background/Aims: Gut microbiota has been reported to correlate with a higher mortality and worse prognosis of cardiovascular diseases. Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite of specific dietary nutrients, which is linked to cardiac fibrosis. Recent reports have sugges...

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Detalles Bibliográficos
Autores principales: Li, Xueling, Geng, Jin, Zhao, Jinxuan, Ni, Qianqian, Zhao, Chenze, Zheng, Yaru, Chen, Xiaomin, Wang, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634262/
https://www.ncbi.nlm.nih.gov/pubmed/31354519
http://dx.doi.org/10.3389/fphys.2019.00866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634262/
https://www.ncbi.nlm.nih.gov/pubmed/31354519
http://dx.doi.org/10.3389/fphys.2019.00866

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