Novel lipophilic SN38 prodrug forming stable liposomes for colorectal carcinoma therapy

Background: SN38 (7-ethyl-10-hydroxy camptothecin), as a potent metabolite of irinotecan, is highly efficacious in cancer treatment. However, the clinical utility of SN38 has been greatly limited due to its undesirable properties, such as poor solubility and low stability. Materials and methods: In...

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Detalles Bibliográficos
Autores principales: Xing, Jing, Zhang, Xiquan, Wang, Zhe, Zhang, Huanqing, Chen, Peng, Zhou, Gaoxin, Sun, Chunlong, Gu, Ning, Ji, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634269/
https://www.ncbi.nlm.nih.gov/pubmed/31371956
http://dx.doi.org/10.2147/IJN.S204965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634269/
https://www.ncbi.nlm.nih.gov/pubmed/31371956
http://dx.doi.org/10.2147/IJN.S204965

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