Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants

Phenylalanine and cysteine comprise common miss-sense variants (i.e., single nucleotide polymorphisms [SNPs]) at amino acid position 254 of the human indole(ethyl)amine-N-methyltransferase (hINMT). The phenylalanine variant, which occurs in linkage disequilibrium with two 3’ UTR SNPs, has been repor...

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Detalles Bibliográficos
Autores principales: Torres, Brian, Tyler, James S., Satyshur, Kenneth A., Ruoho, Arnold E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634407/
https://www.ncbi.nlm.nih.gov/pubmed/31310642
http://dx.doi.org/10.1371/journal.pone.0219664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634407/
https://www.ncbi.nlm.nih.gov/pubmed/31310642
http://dx.doi.org/10.1371/journal.pone.0219664

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