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Assessment of intratumoral heterogeneity with mutations and gene expression profiles

Intratumoral heterogeneity (ITH) refers to the presence of distinct tumor cell populations. It provides vital information for the clinical prognosis, drug responsiveness, and personalized treatment of cancer patients. As genomic ITH in various cancers affects the expression patterns of genes, the ex...

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Detalles Bibliográficos
Autores principales: Sung, Ji-Yong, Shin, Hyun-Tae, Sohn, Kyung-Ah, Shin, Soo-Yong, Park, Woong-Yang, Joung, Je-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634409/
https://www.ncbi.nlm.nih.gov/pubmed/31310640
http://dx.doi.org/10.1371/journal.pone.0219682